Scientist - Cell Based Assay Group
CSL
Australia, Victoria, Parkville
18d ago

The Opportunity

The opportunity exists for an experienced and qualified Scientist to join the Bioassay Group at CSL in Parkville. This is an exciting opportunity for an energized professional with experience in providing and applying well-

developed scientific and technical capability with respect to in vitro assay methodologies.

Reporting to the Manager, Bioassay Group, you will contribute to the maintenance of bioanalytical resources (e.g. source and order reagents / consumables required to support experimental work, prepare laboratory reagents and stock solutions) and provide excellence in the design and performance of experiments and assays.

Key Responsibilities Include :

  • Provide and apply well-developed scientific and technical capability with respect to in vitro assay methodologies (e.g.
  • ELISA, electrochemiluminescence ECL , immunohistochemistry, mRNA and transcript profiling, Western blotting, multiplex bead arrays Luminex / Bioplex , flow cytometry cell phenotyping and receptor binding / occupancy, cell-

    based bioassays apoptosis, proliferation, cytotoxicity etc. )

  • Maintain awareness of key scientific / technical strategies and innovative technical developments in your areas of expertise
  • Previous experience with utilising Design of Experiments (DoE) and automation to expedite assay design and facilitate efficient assay delivery and conduct where appropriate
  • Ensure all documentation and recording of laboratory notes / databases is up to date, secure and accessible in accordance with the applicable standards and guidelines (e.
  • g. Laboratory Workbook usage guidelines, GSP and GMP)

  • Maintain laboratories and storage facilities to GSP principles
  • Mentor appropriate learning and development opportunities for peers and junior team members
  • Ensure high safety standards are practiced within the working environment
  • Conduct and communicate Risk Assessments on chemicals, equipment and procedures
  • Essential Qualifications and Experience :

  • A tertiary degree including Honours (or equivalent), in a scientific / medical / (bio)pharmaceutical discipline
  • Higher postgraduate qualification, e.g., PhD will be well regarded
  • At least three years laboratory experience in pre-clinical and clinical development of biopharmaceuticals or equivalent related experience in industry and / or academic environments
  • Relevant and demonstrated expertise in the following :
  • In vitro assays (e.g. ELISA, electrochemiluminescence ECL , immunohistochemistry, Western blotting, mRNA and transcript profiling, multiplex bead arrays Luminex / Bioplex , flow cytometry cell phenotyping and receptor binding / occupancy, cell-
  • based bioassays apoptosis, proliferation, cytotoxicity etc. , lipoprotein remodelling, cholesterol efflux, contact activation pathway signalling, bradykinin pathway signalling) and the associated instrumentation and software

  • Experience in protein chemistry techniques such as Biacore or in-solution binding analysis would be of advantage
  • Proficient in Microsoft Office and graphics programs (e.g. GraphPad Prism)
  • Experience in writing SOPs, Forms, Scientific / Validation protocols and reports
  • Very good communication and networking skills. The ability to work successfully in a cross-functional, multidisciplinary and multinational team environment.
  • How to Apply :

    Applications must address the selection criteria above and include a current CV and covering letter.

    Applications Close on Friday, 6th July, 2018

    Employment screening, including criminal history, medical assessment, confirmation of experience and stated qualifications, Australian working rights and other relevant checks form part of the candidate suitability

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